When to use lanolin cream When you breastfeed, your baby’s frequent sucking can deplete the natural oils in your skin. This can lead to your nipples feeling sensitive, dry and sore – they may even start to crack. This is where Purelan 100 lanolin cream comes in by helping to replenish these oils. And of course, you don’t have to wait until you’re experiencing sore or cracked nipples before using nipple cream – you can apply it as a gentle moisturizer to help the skin on your breasts feel softer and more supple, before or after breastfeeding.